Sampling properties of homozygosity-based statistics for linkage disequilibrium
نویسندگان
چکیده
منابع مشابه
Sampling properties of homozygosity-based statistics for linkage disequilibrium.
Homozygosity-based statistics such as Ohta's identity-in-state (IIS) excess offer the potential to measure linkage disequilibrium for multiallelic loci in small samples. However, previous observations have suggested that for independent loci, in small samples these statistics might produce values that more frequently lie on one side rather than on the other side of zero. Here we investigate the...
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ژورنال
عنوان ژورنال: Mathematical Biosciences
سال: 2007
ISSN: 0025-5564
DOI: 10.1016/j.mbs.2006.07.001